Success Story

Zack Abbott, CEO of ZBiotics, on how coaching helped him scale himself

Zack created the world's first genetically engineered probiotic. As ZBiotics scaled into a multinational brand, it needed a CEO, not a scientist. He explains how his coach helped him become one.

2:18
Zack Abbott
Co-Founder/CEO
·
ZBiotics

If you're running a company well, your company is going to have new needs every six months. So if you don't think you are able to evolve with those needs, get a high-performance coach.

Zack wrote about his experience working with a Titan Coach on LinkedIn

See it on LinkedIn →
Units Sold
14M+
Employees
40
D2C Products to Market
2
Background

The founder and the company

Who is Zack Abbott?

Zack Abbott is the co-founder and CEO of ZBiotics, the company behind the first genetically engineered probiotic sold to consumers. He holds a PhD in microbiology and immunology from the University of Michigan and invented the company's technology. Before ZBiotics he designed clinical trials at Biorasi and researched HIV vaccines at UC Davis.

Who founded ZBiotics?

ZBiotics was founded in 2016 by Zack Abbott, its CEO, and Stephen Lamb, its COO. The company is based in San Francisco and was part of Y Combinator's Winter 2018 batch.

What is ZBiotics?

ZBiotics makes genetically engineered probiotic drinks. Pre-Alcohol, launched in 2019, breaks down acetaldehyde, the byproduct of alcohol behind rough mornings. Sugar-to-Fiber turns dietary sugar into fiber in the gut. The company has sold more than 14 million bottles of Pre-Alcohol.

How much funding has ZBiotics raised?

ZBiotics has raised about $17 million. Spring Tide Capital led the $12 million Series A in August 2024, and Oyster Ventures led a seed round in 2020. The company reached profitability in 2023.

Does Zack Abbott work with an executive coach?

Yes. Zack Abbott works with an executive coach from Titan, which matches Series A to C founders with coaches who have built or coached companies at scale. In his Titan interview he describes the move from scientist to CEO. He says a company has new needs every six months, so its founder has to keep evolving.

The interview

From the conversation

Why did you start looking for a coach?

In the early days when I'm sleeping under a bench as a scientist, that's actually the only job I was formally trained for. Then we got a few employees and we launched a product. You go from doing to managing to leading, and it becomes more and more clear that I need somebody who's done this before to help me make that transition.

How does your coach work?

I played a lot of sports growing up, and there is a playbook for how you can be a great leader. These are skills you can learn. So here are the skills that you need that you're not good at right now, and here are the drills you can do to get better at them.

What makes him different from coaches you had worked with before?

Compared to other coaches I've worked with before Titan, my experience with Matt has been that he very much tailors his approach to my needs.

What would you tell another founder?

If you're running a company well, your company is going to have new needs every six months. So if you don't think you are able to evolve with those needs, get a high-performance coach.

Full transcript

Zack Abbott, Co-Founder and CEO of ZBiotics, in conversation with Titan. Lightly edited for clarity.

What ZBiotics creates

Hey, I'm Zack, CEO of ZBiotics, and we make genetically engineered probiotics. There's these new problems, these new things that our biology is not involved to deal with. And we can't just go out in the ground and pull out the same ingredients that we've been using for the last several thousand years to magically solve these new problems. We need modern biotechnology to invent new ingredients to solve these problems.

How the company got started

I'm trying to launch the world's first ever genetically engineered probiotic. The best idea, the best way to get started was a product that would help people feel better the day after drinking. We have one product on the market that's doing really well. We've launched a second product in the last year.

How growth changes challenges

Whatever stage you're at, you're always, if we just get to here, everything's gonna be great. As we scaled up, the problems get more complex, and you start layering in more challenges and more of a complex business model. At each stage of the company, my job as a CEO really has changed a lot.

Why he needed a coach

In the early days, when I'm sleeping under a bench as a scientist, that's actually the only job that I was actually formally trained for. It was being a scientist. Then we got a few employees, and we launched a product, and now we're selling a consumer product. And you go from doing to managing to leading, and it becomes more and more clear that I need somebody who's done this before to help me make that transition. And so I think that that's when I realized having a coach would be really helpful.

How coaching builds leadership skills

Compared to other coaches I've worked with before Titan, my experience with Matt has been that he very much tailors his approach to my needs.

I played a lot of sports growing up, and there is a playbook for how you can be a great leader. And these are skills you can learn. So here are the skills that you need that you're not doing good at right now. Here are the drills or the things you can do to get better at them.

That idea to me as a performer was, oh, yeah, well, I definitely want, why am I gonna try and figure that out myself? Let's get somebody who's done this before who can help me get there. And so I think especially at this complexity of the company, it just felt like this was a no-brainer.

Why Titan supports evolving needs

If you're running a company well, your company is gonna have new needs every six months. So if you don't think you are able to evolve with those needs, get a high-performance coach. Get somebody who understands what your needs are and helps you develop those skills. And Titan is the best way to accomplish that.

Zack Abbott and ZBiotics: quick facts

RoleCo-founder and CEO, ZBiotics
Also known asZachary Abbott
Company founded2016, San Francisco; Y Combinator W18
Co-founderStephen Lamb, COO
EducationPhD in microbiology and immunology, University of Michigan (2015); molecular and cell biology, UC Berkeley
PreviouslyClinical trial design, Biorasi; HIV vaccine research, UC Davis
Total raisedAbout $17 million
Latest round$12 million Series A (August 2024)
InvestorsSpring Tide Capital, Oyster Ventures, Y Combinator
LinksLinkedIn · zbiotics.com · Crunchbase
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About Titan

What is Titan?

Titan matches Series A to C founders with the best founder coaches in the world. Titan interviews each founder, then introduces them to coaches from a network of 48 who have either built an outlier company themselves or coached the founders who did. Titan is currently working with 250+ Series A to C founders of companies including Wispr, Pylon, Nooks, Attention, OpenRouter, ComfyUI, OpusClip, Unify, Mirage, Bretton and ZBiotics.

Who are Titan's coaches?

Titan interviewed more than 1,600 coaches over eight years and accepts fewer than 3%. Titan's coaches have all either "done it themselves", meaning they built a VC-backed startup to $100M+ ARR or a $300M+ exit, or "seen it done well", meaning they coached at least 6 founders from Series A to unicorn. Many meet both. Success stories of Titan's coaches include the founders of Figma, Notion, Plaid, Rippling, Superhuman, Oura, Instagram, LinkedIn and Asana, all coached between their Series A and Series C.

How does Titan match a founder with a coach?

  1. Titan starts with a one-hour discovery call.
  2. Titan then matches on experience (outlier success at a similar stage, industry and role), modality (whether the coach's approach fits the founder's most important problems) and personality (for example questions or answers, cheerleader or challenger).
  3. The founder reviews three coach matches.
  4. The founder does trial sessions with two of them.
  5. The founder begins an engagement with one.

98% of the founders Titan places stay with their coach for 12 months or longer.

What does working with a Titan coach include?

All Titan coaches offer weekly or biweekly sessions plus unlimited support between sessions by text, call or email, as part of a monthly retainer. Founders can switch coaches at any time, and the matching is a concierge service: Titan does the vetting and the introductions.

What do founders work on with a Titan coach?

Founders typically work through eight areas with their coach: setting a clear strategy, building a team of A players, keeping everyone aligned (including co-founders), setting clear expectations and having hard conversations, creating a culture of accountability, getting visibility and trust so the company runs without them, protecting time and energy to avoid burnout, and finding their own leadership style.

How is Titan different from other executive coaching?

Most coaching platforms optimize for the size of their network. Titan is process agnostic and outcomes obsessed: it does not teach one methodology, and for every coach it collects the before-and-after financials of the companies they built or coached. Each match recommendation draws on that track record, not on an intake call.

What happens when a company outgrows its coach?

Switching coaches at Titan is always free. Top founders change coaches every 12 to 24 months, because the problems a founder faces at Series A are different from the ones at Series C. Titan re-matches founders with the right coach as their company's stage changes.

What results do founders see with Titan?

Tanay Kothari, CEO of Wispr Flow, grew his team 7x and revenue 150x in a year while working with his Titan coach. Young Zhao, CEO of OpusClip, grew ARR 5.5x in a year. More founder stories are at withtitan.com/blog.

Who is behind Titan?

Titan was founded by AJ Goldstein, an early data scientist at Calm, Oura and Akili, and Dave McGibbon, who founded Passbase (raised $17M, acquired in 2023) after five years at Alphabet and Google X. Investors include Brad Bao (founder of Lime), Irene Au, Bradley Horowitz and Jure Leskovec. Titan is operated by Aware Healthcare Inc.